Evidence Vault
Activate and Monetize Your Patients’ Clinical Data, On Your Terms.
Powered by 3Aware, the Evidence Vault enables health systems to participate in industry-funded studies and internal research without relinquishing control of their patients' data. No data leaves your environment. Governance stays with you. Analytic processing remains inside your secure cloud infrastructure.

Built for your control, governance, and secure participation
Data remains within your secure infrastructure
All processing occurs within your secure infrastructure
You approve de-identification with expert determination
Exported outputs remain under your governance
By default, no commingling data with other institutions
3Aware pays you royalties and covers cloud costs associated with participation in our commercialization network
On Your Terms
The 3Aware Evidence Vault is a highly secure cloud-based appliance embedded within your existing environment. It enables your institution to activate de-identified clinical data for research and sponsored studies while maintaining control over how data is processed, governed, and used.
Your institution decides:
What data is included
How de-identification is handled
What research is permitted
What results can be exported
Whether to participate in collaborative studies
This isn’t data brokerage—it's a governed, federated evidence engine. The 3Aware Comprehensive RWE Generation and Analytic Solution lives within the Embedded Vault, turning clinical data into a scalable research and revenue-generating asset for health systems.
We do the heavy lifting. So, you don't have to.
3Aware conforms to your ecosystem, and does the heavy lifting.
So you don’t have to.
The 3Aware Evidence Vault accesses the clinical data through a simple ETL process.
All you do is provide the extract. We do the rest.
To facilitate deployment, 3Aware conforms to your:
Existing cloud infrastructure
Preferred data ontologies
Preferred data extract format
IRB approved data standards
Enterprise architecture standards
Self-service data analysis infrastructure
3Aware Evidence Vault
The 3Aware Evidence Vault helps health systems transform underutilized clinical data into a strategic asset for internal research, external sponsored studies, and long-term institutional value.
Embedded directly within your existing infrastructure, the Vault enables secure analysis of structured and unstructured clinical data while preserving your governance. That means your institution can support high- value research opportunities, generate new non-reimbursement revenue streams, and expand publication potential — without transferring raw patient-level data outside your environment.
3Aware manages commercialization on your behalf, connecting your institution to established demand from MedTech manufacturers and facilitating sponsored research opportunities from paid feasibility through full study execution.
A Network Model Built for Institutional Control
Each 3Aware Evidence Vault operates as its own isolated environment, with no commingling of data, processing, or outputs across participating health systems.
Institutions may also choose to participate in optional collaborative research across a broader network of Vaults. When enabled, this model allows participating health systems to support multi-site studies using de-identified structured and unstructured clinical content under its own institution-defined governance rules.
Each health system decides if, when, and how it participates.
That means you retain control over:
Study participation
Permitted analyses
Export rules
Governance requirements
Scope of collaboration
Why It Matters for Health Systems
Health systems generate enormous volumes of clinically rich data, but much of that value remains difficult to operationalize. Fragmented systems, unstructured records, governance requirements, and limited internal bandwidth often prevent institutions from turning data into scalable research and strategic value.
At the same time, MedTech manufacturers and other life science companies are investing heavily in real-world evidence and actively seeking health system partners with the clinical depth to support high-quality research which is often driven by regulatory requirements.
The 3Aware Evidence Vault connects these needs through a model that allows your institution to:
Activate existing clinical data for research use
Participate in sponsored studies without giving up data control
Generate incremental non-reimbursement revenue
Accelerate internal research and publication opportunities
Strengthen institutional eminence through high-value external collaboration
How It Works
Step 1: Deploy Within Your Environment
3Aware embeds a highly secure cloud-based appliance directly within your existing infrastructure.
Step 2: Activate Your Clinical Data for Research
Structured and unstructured clinical data is organized and enabled for research use inside your environment.
Step 3: Maintain Institutional Governance
Your team defines the rules for access, use, analysis, and approved outputs.
Step 4: 3Aware Brings the Demand
3Aware identifies sponsored study opportunities, connects your institution with industry demand, and managess commercialization and project coordination.
Step 5: Generate Evidence, Revenue and Institutional Value
Support internal and sponsored studies that lead to new evidence, new revenue streams, peer-reviewed publications, and broader institutional visibility.
3Aware Evidence Vaults Enable:
For Health Systems
- Maintain Full Control
- Take Advantage of Established 3Aware Commercial Network
- Generate Revenue
- Accelerate Research
- Enhance Eminence
For Industry
- Access De-Identified RWD
- Utilize Best-In-Class Analytics
- Discover Landmark Findings
- Generate Regulatory-Grade RWE
- Optimize Product Performance
Build the Infrastructure for the Next Generation of Clinical Research
The 3Aware Evidence Vault gives health systems a new way to participate in high-value research — securely, selectively, and under their own governance. Ready to begin? Join the network of 3Aware Evidence Vaults and unlock new research and revenue opportunities. Turn existing clinical data into long-term strategic research infrastructure.
Questions? Email us at info@3aware.ai

